The host cytokine response toPorphyromonas gingivalisis modified by gingipains

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The host cytokine response to Porphyromonas gingivalis is modified by gingipains.

BACKGROUND/AIMS Clinical studies indicate that primary proinflammatory cytokines, such as interleukin-1beta (IL-1beta) are elevated in the gingival crevice around teeth with periodontitis but the secondary cytokines and chemokines, IL-6 and IL-8, are not. The human gingival epithelial cells (HGECs) lining the gingival sulcus respond to perturbation by microbes of dental plaque by releasing a wi...

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ژورنال

عنوان ژورنال: Oral Microbiology and Immunology

سال: 2009

ISSN: 0902-0055,1399-302X

DOI: 10.1111/j.1399-302x.2008.00467.x